), and cancer cells cant do this, Therefore, healthy cells are more resilient to the cancer treatment, Once Rhonda has stopped breast feeding her son, she plans to start regularly doing some long term fasts (2 days minimum), The gene that is important in determining whether you will experience placebo vs. nocebo, also controls the degradation of, People with less dopamine, are more likely to experience the nocebo response, Some schizophrenics are prescribed a very high dose (3-6 grams a day) of fish oil because their dopamine is lower in the prefrontal cortex, which is associated with he negative symptoms of schizophrenia, Rhonda takes capsulized fish oil from a friend who makes it in Norway she takes 5-6 grams a day (6 pills for her), Joe is favorable of it, but he eats too much meat (elk) to stay in ketosis, The same thing with being in ketosis, youll have BHB molecules in your blood, Short answer we dont know how similar BHB is to butyrate, so its tough to say, Perhaps the glucose in her brain is being spared for other things besides worrying, Joe suggests the perfect pre podcast meal the, Shell often take it before doing a podcast, or a big talk, It lowers her blood sugar levels pretty dramatically, so once the ketones ware off (after a couple of hours) she crashes, since she doesnt follow a ketogenic diet regularly, If she was already in ketosis, this wouldnt happen, Perhaps the crash could also be mitigated by consuming the HVMN with a higher carb meal, Brussel sprouts also contain sulforaphane, You cant cook the sprouts the enzyme that converts the precursor into active sulforaphane is heat sensitive, The mustard powder has the active enzyme that converts the precursor in the sprouts/kale into sulforophane, Rhonda has been taking 3 pills/day, each pill is 10mg with food, You get 2 copies of every gene 1 from mom, 1 from dad, The gene also increases the chances of a poor outcome if you have any kind of traumatic brain injury (TBI), If you have ApoE4. Then I became a mom. Rogan has been criticized for making public remarks about the vaccine which many deem irresponsible and potentially even dangerous, given his enormous platform. No credit card needed. . I have to go to bed immediately. It appears to me that Dr. Patrick might not be a true physiology nerd, and I am looking for counter arguments. About 300 different genes were different in how they were/were not activated in the sperm DNA of the obese men. doesn't how usually worship at her altar and spread the good word of Dr. Rhonda Patrick? Dr. Rhonda Patrick on Vaccine Misinformation and Long-haul Covid Rhonda Patrick Supplements - What Does She Take? - Drug Genius "If you look at the data, young people are also experiencing those things at a higher rate," she said. Dr. Rhonda Patrick on Vaccine Misinformation and Long-haul Covid - YouTube 0:00 / 14:54 Get the latest information from the CDC. M2EwNzZlZTA1YmU3MmYwNzEwZDM3NTFkMThjZDZhYWUwM2YyMjJmOTUxNTFk "If you want to only worry about yourself and not society, then that's OK," Fauci said of Rogan. To help support the investigation, you can pull the corresponding error log from your web server and submit it our support team. we need to fix this, Even a degree in nutrition has flaws as a lot of the dogma has changed and they are not often very hardcore science in their focus, Rhonda keeps switching her fields from chemistry, aging, cancer, nutrition and the brain, This helps you have new perspectives that people who only do one thing dont see, Consumer focused blood tests on all blood markers (e.g. 0:00 / 24:29 Joe Rogan - Dr. Rhonda Patrick on the Carnivore Diet JRE Clips 6.95M subscribers Subscribe 43K Share 3.1M views 4 years ago Show more Show more Joe Rogan Reports Back. Exercise is awesome of TONS of reasons, just do it!!! Rogan: If youre looking at your screens do you use blue-light blocking glasses? In a previous episode of his show, he said that he didn't believe people who were young and healthy didn't need to get vaccinated, a claim which Dr. Anthony Fauci called "incorrect". ZWJmNjMxNjA3YjUzNTdiODRlZTA1N2M2OGVhMDI4ZDgzNDdhYWY2YTI3YzIw eyJtZXNzYWdlIjoiYWRmN2ZhMjQ4MjRjYTdiNzUwMzY3YTgyMDc3ZTMwMmMy You know like when youre working out hard sometimes you require more sleep? MTE4YzU2NzFiN2UzYTBmMGZkYjA2N2YzN2IyZjkyOThjZjE4ZDU0MzlhYTBl When I do squats for sure. NzQzOGNmNDgyMjllYjIwNWRmZWYxNTQwYjI4ZjdiMTBkNmNlMWNhZTA2MGU0 ZDA1MDBmMTcyYmJkZGI0OWQxYWZhOGJkOGQ4N2Q4NjA0MTY0ZTRhYzZkYzcz Exercise increases the production of serotonin, and beta-endorphins. Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Rhondas podcast with Stanford microbiome experts, the Sonnenburgs, NFL rookie retiring at 24 because the next hit might kill me, (SEE CROSS Post from RHONDAs Podcast with the Sonnenburgs Gut Bacteria Experts from Stanford), Risk even higher with APOE4 genetic risk factors, Aim to get all the vitamins/minerals you need, MMA felt very tribal which was unique/cool vs. other sport events, The amount of likely brain damage (e.g. This product is used both by Joe Rogan and Dr. Rhonda Patrick, but Patrick utilizes the mushroom in periods of intense writing or creative work according to the podcast. Philip Ellis is a freelance writer and journalist from the United Kingdom covering pop culture, relationships and LGBTQ+ issues. Patrick: I used to never get sick. NTNkNWIzNzc5MWUwMjI1NjY2NTQwZGM1NDk0ZjE4NjNjNmY5ZTk2ZDdiMDFk Podcast Notes is a Signal From the Noise LLC Production, All Right Reserved, Berkshire Hathaway Annual Shareholders Meeting, Christopher Lockhead's Follow Your Different, Everyday Espionage Podcast with Andrew Bustamante, Feel Better, Live More With Dr. Rangan Chatterjee, Logocentrifugal Podcast With Chance Lunceford, Moonshots and Mindsets with Peter Diamandis, Network State Podcast with Balaji Srinivasan, Spearhead with Naval Ravikant and Babak Nivi, The Jolly Swagman Podcast with Joseph Walker, The Underworld Podcast with Danny Gold and Sean Williams, The Unraveling Podcast with Jocko Willink and Darryl Cooper, This Week in Startups with Jason Calacanis, Where It Happens with Sahil Bloom and Greg Isenberg, Sauna: if you have access use the sauna regularly to improve cardiovascular health and immune functions take a hot bath if you dont have access, Theres a big difference between oral vitamin C and Intravenous vitamin C, You can take vitamin C orally but will need a big dose and it still wont have the same effect; IV once per week if you can, Sleep plays a crucial role in immunity, homeostasis, and regulation of body functions, People are actively working on monoclonal antibodies, Improved therapeutic treatments coming, including more repurposing of drugs that will make things less scary, As you get older your immune system declines, There are lifestyle components of immune system you can be proactive about: exercise, sleep, supplements, nutrition, gut-microbiome health, Besides age, the major regulator of immune function seems to be previous virus exposure, not genetics, At any given point you have antibodies against 10 different viruses but youre not always getting sick, 50-80% of US population has had CMV and most people dont ever know they have had it and show no symptoms, CMV impacts immune function differently depending on when you get it, When youre young, it enhances immune response but for older people its deleterious, Interesting tie-in to COVID-19 because we know older people are more prone to severity, Its likely that theres some cross-immunity happening since SARS-COV-2 viruses is part of beta coronaviruses along with SARS-CoV-1 and MRSA, 15-30% of common colds come from coronaviruses so theres a good hypothesis that potentially one or two of common cold virus antibodies could interact with SARS-CoV-2 and neutralize it, Antibody binds to virus and instead of neutralizing it, changes the configuration so the virus can get into the cell better, This activates the immune system and causes pathology, This results in a higher viral load without antibodies to neutralize, Weve seen it happen with coronaviruses, including SARS-CoV-1 and MRSA, The spike region is where antibodies bind and is also the region the virus uses to get into the cell, Currently seeing two major strain mutations in the spike regions one mutation more prominent in Asia, one mutation more predominant in Europe and North America, Brings to light an interesting genetic link to mutations, Theres a theory that the mutation is causing peoples immune system to become more active and lead to severe COVID-19, Monoclonal antibodies: identify specific antibody that binds to spike protein and manufacture them, Problem is this will offer short lived protection since you are not making your own antibodies as you would with a vaccine, Continuous exploration into repurposing drugs and combination drug treatments, Anecdotally, the majority of people on ventilators die partly because ventilators cause more damage to the lungs and can induce more damage, But its hard to say which came first did the ventilator do the damage or was the damage so severe that the patient needed a ventilator, People with Type O blood seem to be less susceptible to contracting COVID-19, People with Type O blood create Type A antibodies which bind to spike region and neutralize antibody so it cant enter the cell, We saw this in SARS-CoV-1 so maybe same for SARS-CoV-2, Another (unproven) theory: Type O blood people have lower levels of blood factor involved in clotting, Hearing more stories that some prisoners are trying to contract SARS-CoV-2 to get out of jail by spitting in a cup and passing to others, First off, its important to distinguish between asymptomatic and pre-symptomatic, Some people do not have symptoms at the time of testing but develop symptoms later so are actually pre-symptomatic, Its possible that viruses have already gone around that environment so antibodies from those viruses are helping in immunity from SARS-CoV-2, Rhonda was also searching to literature to see whether inmates are vaccinated prior to entering but couldnt find that information, Poor sleep has a huge impact on glucose and spikes and also plays a role in maintaining optimal immune functions, Rhonda takes melatonin to help her sleep, 10 mg/day, Regulating circadian rhythm is crucial for sleep, Rhonda makes sure to have bright light exposure in the morning (e.g., opening curtains, walking outside), and changes the lighting in the house in the evening to red lights, 70% of US population has insufficient Vitamin D levels; 28% are deficient, Body can generate naturally when exposed to sun daily, Obese people in US are also more likely to be vitamin D deficient, Genetic polymorphisms: people that have variations in genes that cause them to have less vitamin D, These people are more likely to die from respiratory infection, African Americans in the US are 28x more deficient in vitamin D than Caucasians, A recent study that looked at COVID-19 patients observed an inverse relationship between vitamin D levels and COVID-19 symptoms: the lower the vitamin D levels, the higher the severity of COVID-19, In Indonesia almost all patients that died from COVID-19 were vitamin D deficient, Melanin blocks ability to produce Vitamin D, In the US and Europe, African Americans and black people are more likely to die from COVID-19, Even when adjusting for SES and lifestyle factors, this was still true so something else must be happening, Tolerable upper intake is 4000 IUs per day but its best to get vitamin D blood test to measure levels, There are clinical studies exploring the role of vitamin D but not many in the US, Rhonda wants to see nurses and first responders take vitamin D to see the role in prevention but those studies are not being done, Joe uses the sauna 7 days/week, 180-degrees for 25 min, Rhonda uses the sauna 5 days/week, 180-degrees for 25 min, Heart rate variability improves, blood pressure goes down, cardiovascular health improves, all-cause mortality decreases, Sauna use also improves immune system and makes you more resilient against infection, Brain-derived neurotropic factors (BDNF) increases with exercise and heat stress (sauna), The positive benefits of physical activity on the cardiovascular system were enhanced when sauna was added, Sauna use increases heat shock proteins which prevent muscle atrophy, neurodegenerative genes, and have anti-depressant effects, People who sat in 160-degree sauna for 30 minutes had a 60% increase in heat shock protein compared to baseline, Large Harvard study being done to assess whether hot yoga increases heat shock protein, Heat shock protein have antiviral activity against influenza A, Regular sauna is heating ambient air which in turn raises core body temperature, Infrared saunas are directly heating body without heating the ambient air for example, in a heating tent or blanket, We know more about the effects of dry sauna, For people who dont have access to sauna, a hot bath is a good modality for heat shock protein, Studies being done to assess whether sauna can have anti-depressant effect on depressed patients, Saunas could also provide an avenue for giving sedentary and disabled people the benefits of physical activity without exercising, Ice baths and cold showers can be comparable to cryotherapy but you have to stay in the cold water longer, Cold shock protein hasnt really been measured in humans, instead whats measured is norepinephrine which has been shown to increase, Cold shock protein and hot shock protein have been shown to improve mood as well, The pharmacokinetics of vitamin C are very different in oral vs IV consumption, Oral vitamin C is good for immune function, etc.

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